Publications

Scopus Author Profile

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PEER-REVIEWED PUBLICATIONS

Chandler PD, Clark CR, Zhou G, Noel NL, Achilike C, Mendez L, Ramirez AH, Loperena-Cortes R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Qian J, Schully S, Ratsimbazafy F, Mockrin S, Gebo K, Dedier JJ, Murphy SN, Smoller JW, Karlson EW; All of Us Research Program Investigators (2021) Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research. Scientific Reports. 11(1):12849

Julian TH, Glascow N, Barry ADF, Moll T, Harvey C, Klimentidis YC, Newell M, Zhang S, Snyder MP, Cooper-Knock J, Shaw PJ (2021) Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes. EBioMedicine. In Press.

Follis S, Klimentidis YC, Bea J, Hu C, Garcia D, Wactawski-Wende J, Kohler L, Shadyab AH, Flores M, Tindle HA, Chen Z (2021) The intersectional role of social stress in fracture risk: results from the Women's Health Initiative. Journal of Epidemiology and Public Health. In press.

Florea A, Jacobs ET, Harris RB, Klimentidis YC, Thajudeen B, Kohler LN (2021) Chronic kidney disease unawareness and determinants using 1999-2014 National Health and Nutrition Examination Survey Data. Journal of Public Health. In press  

Catalfamo CJ, Heslin KM, Shilen A, Khan SM, Hunsaker JR, Austhof E, Barraza L, Cordova-Marks FM, Farland LV, Garcia-Filion P, Hoskinson J, Jehn M, Kohler LN, Lutrick K, Harris RB, Chen Z, Klimentidis YC, Bell ML, Ernst KC, Jacobs ET, Pogreba-Brown K (2021) Design of the Arizona CoVHORT: A Population-Based COVID-19 Cohort. Frontiers in Public Health. 9:620060.

Zhang X, Theodoratou E, Li X, Farrington SM, Law PJ, Broderick P, Walker M, Klimentidis YC, Rees JMB, Houlston RS, Tomlinson IPM, Burgess S, Campbell H, Dunlop MG, Timofeeva M. (2021) Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study. Br J Cancer. 124 (7): 1330-1338.

Franchetti MK, Bharadwaj PK, Nguyen LA, Van Etten EJ, Klimentidis YC, Hishaw GA, Trouard TP, Raichlen DA, Alexander GE (2020) Interaction of Age and Self-reported Physical Sports Activity on White Matter Hyperintensity Volume in Healthy Older Adults. Frontiers in Aging Neuroscience. 12:57602.

 

Florea A, Harris RB, Klimentidis YC, Kohler LN, Jurutka PW, Jacobs ET (2020) Circulating Fibroblast Growth Factor-21 and Risk of Metachronous Colorectal Adenoma. Journal of Gastrointestinal Cancer. In press.

Santos EM, Coalson JE, Munga S, Agawo M, Jacobs ET, Klimentidis YC, Hayden MH, Ernst KC."After those nets are torn, most people use them for other purposes": an examination of alternative bed net use in western Kenya (2020). Malaria Journal. 19(1):272.

Klimentidis YC, Arora A, Newell M, Zhou J, Ordovas JM, Renquist BJ, Wood AC (2020) Phenotypic and Genetic Characterization of Lower LDL-C and Increased Type-2 Diabetes Risk in the UK Biobank. Diabetes. 69(10):2194-2205.

Furlong MA, Klimentidis YC (2020) Associations of Air Pollution With Obesity and Body Fat Percentage, and Modification by Polygenic Risk Score for BMI in the UK Biobank. Environmental Research. 185:109364.

Santos EM, McClelland DJ, Shelly CE, Hansen L, Jacobs ET, Klimentidis YC, Ernst KC. (2020) Malaria Education Interventions Addressing Bed Net Care and Repair Practices: A Systematic Review. Pathogens and Global Health. 114(1):2-15

Morrill KE, Lopez-Pentecost M, Ballesteros G, Pfander JL, Hingle MD, Klimentidis YC, Thomson CA, Garcia DO (2019) Weight loss interventions for Hispanic women in the USA: a protocol for a systematic review. Syst Rev. 8(1):301

German CA, Sinsheimer JS, Klimentidis  YC, Zhou  H, Zhou JJ (2020) Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale. Genetic Epidemiology. 44(3):248-260.

Santos EM, Coalson JE, Jacobs ET, Klimentidis YC, Munga S, Agawo M, Anderson E, Stroupe N, Ernst KC (2019) Bed net care practices and associated factors in western Kenya. Malar J. 14;18(1):274

Follis SL, Bea J, Klimentidis YC, Hu C, Crandall CJ, Garcia DO, Shadyab AH, Nassir R, Chen Z (2019) Psychosocial stress and bone loss among postmenopausal women: results from the Women's Health Initiative. J Epidemiol Community Health. 73(9):888-892

Raichlen DA, Klimentidis YC, Bharadwaj PK, Alexander GE (2019) Differential associations of engagement in physical activity and estimated cardiorespiratory fitness with brain volume in middle-aged to older adults. Brain Imaging Behav. In press.

Choi KW, Chen CY, Stein MB, Klimentidis YC, Wang MJ, Koenen KC, Smoller JW; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019) Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study. JAMA Psychiatry. In Press.

Bhagwandin C, Ashbeck EL, Whalen M, Bandola-Simon J, Roche PA, Szajman A, Truong SM, Wertheim BC, Klimentidis YC, Ishido S, Renquist BJ, Lybarger L (2018) The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner. PLoS One. 13(10):e0204898.

Raichlen DA, Klimentidis YC, Hsu CH, Alexander GE (2018) Fractal complexity of daily physical activity patterns differs with age over the lifespan and predicts mortality in older adults. Journal of Gerontology: Medical Sciences. In Press.

Cardel MI, Lemas DJ, Lee AM, Miller DR, Huo T, Klimentidis YC, Fernandez JR (2018) Taq1a polymorphism (rs1800497) is associated with obesity-related outcomes and dietary intake in a multi-ethnic sample of children.  Pediatr Obes. Sep 25.

Klimentidis YC, Raichlen DA, Bea J, Garcia DO, Wineinger NE, Mandarino LJ, Alexander GE, Chen Z, Going SB (2018) Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. International Journal of Obesity. 42: 1161–1176.

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Bea J. Wassertheil-Smoller S, Wertheim B, Klimentidis YC, Chen Z, Zaslavsky O, Manini T, Womack C, Kroenke C, LaCroix A, Thomson C (2018). Associations between ACE-inhibitors, angiotensin receptor blockers and lean body mass in community dwelling older women. Archives of Gerontology and Geriatrics. 19:8491092.

 

Chen Z, Klimentidis YC, Bea JW, Ernst KC, Hu C, Jackson R, Thomson CA (2017). Body Mass Index, Waist Circumference and Mortality in a Large Multiethnic Postmenopausal Cohort - Results from the Women’s Health Initiative. Journal of the American Geriatrics Society. 65(9): 1907-1915.

 

Lemas DJ, Klimentidis YC, Aslibekyan S, Wiener HW, O'Brien DM, Hopkins SE, Stanhope KL, Havel PJ, Allison DB, Fernandez JR, Tiwari HK, Boyer BB (2016). Polymorphisms in stearoyl CoA desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people. Mol Nutr Food Res. 60(12):2642-2653.

 

Klimentidis YC, Arora A, Zhou J, Kittles R, Allison DB (2016). The genetic contribution of West-African ancestry to protection against central obesity in African-American men but not women: results from the ARIC and MESA studies. Frontiers in Genetics. fgene.2016.00089.

 

Klimentidis YC, Arora A (2016) Interaction of Insulin Resistance and Related Genetic Variants with Triglyceride-Associated Genetic Variants. Circulation: Cardiovascular Genetics. 9(2): 154-161.

 

Klimentidis YC, Bea JW, Thompson P, Klimecki WT, Hu C, Wu G, Nicholas S, Ryckman KK, CHARGE Consortium Musculoskeletal Working Group, Chen Z (2016) Genetic Variant in ACVR2B Is Associated with Lean Mass. Medicine & Science in Sports & Exercise. 48(7): 1270-1275.

 

Duarte CW, Klimentidis YC, Harris JJ, Cardel M, Fernández JR (2015) Discovery of phenotypic networks from genotypic association studies with application to obesity. International Journal of Data Mining and Bioinformatics. 12(2): 129-143.

 

Reynolds RJ, Vazquez AI, Srinivasasainagendra V, Klimentidis YC, Bridges SL Jr, Allison DB, Singh JA (2015) Serum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index. Rheumatology International. 36(2): 263-270.

 

Klimentidis YC, Arora A, Chougule A, Zhou J, Raichlen D. (2015) FTO association and interaction with time spent sitting. International Journal of Obesity. 40(3):411-6..

 

Hibler EA, Klimentidis YC, Jurutka PW, Kohler LN, Lance P, Roe DJ, Thompson PA, Jacobs ET (2015) CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence. Nutrition and Cancer. 67(7):1131-41.

 

Klimentidis YC, Chougule A, Arora A, Frazier-Wood AC, Hsu CC. (2015) Triglyceride-increasing alleles associated with protection against type-2 diabetes. PLoS Genetics. 11(5):e1005204.

 

Vazquez AI, Klimentidis YC, Dhurandhar EJ, Veturi YC, Pérez-Rodríguez P. (2015) Assessment of Whole-Genome Regression for Type II Diabetes. PLoS One. 10(4):e0123818.

 

Klimentidis YC, Bea JW, Lohman T, Hsieh PS, Going S, Chen Z. (2015) High genetic-risk individuals benefit less from resistance exercise intervention. International Journal of Obesity. 39(9):1371-5.

 

Lebrón-Aldea D, Dhurandhar EJ, Pérez-Rodríguez P, Klimentidis YC, Tiwari HK, Vazquez AI (2015) Integrated genomic and BMI analysis for type-2 diabetes risk assessment. Frontiers in Genetics. 6:75.

 

Klimentidis YC, Chen Z, Arora A, Hsu CH (2014). Association of physical activity with lower type 2 diabetes incidence is weaker among individuals at high genetic risk. Diabetologia. 57(12):2530-2534.

 

Klimentidis YC, Zhou J, Wineinger NE (2014). Identification of allelic heterogeneity at type-2 diabetes loci and impact on prediction. PLoS One. 9(11):e113072.

 

Klimentidis YC, Wineinger NE, Vazquez AI, De los Campos G (2014). Multiple metabolic genetic risk scores and type 2 diabetes risk in three racial/ethnic groups. Journal of Clinical Endocrinology and Metabolism. 99 (9):E1814-E1818.

 

Chen GB, Liu, N, Klimentidis YC, Zhu Z, Zhi D, Lou, XY (2014). A unified GMDR method for detecting gene-gene interactions in family and unrelated samples with application to nicotine dependence. Human Genetics. 133(2):139-50.

 

Klimentidis YC, Lemas DJ, Wiener HH, O’Brien DM, Havel PJ, Stanhope KL, Hopkins SE, Tiwari HK, Boyer BB (2014). CDKAL1 and HHEX are associated with type-2 diabetes-related traits among Yup’ik people. Journal of Diabetes. 6 (3): 251-259.

 

Klimentidis YC, Vazquez AI, De los Campos G, Allison DB, Dransfield M, Thannickal VJ (2013). Heritability of pulmonary function estimated from pedigree and whole-genome markers. Frontiers in Genetics. 4:174.

 

De los Campos G, Vazquez AI, Fernando RL, Klimentidis YC, Sorensen D (2013). Prediction of Complex Human Traits Using the Genomic Best Linear Unbiased Predictor. PLoS Genetics. 9 (7), e1003608.

 

Aslibekyan S, Vaughan LK, Wiener HW, Lemas DJ, Klimentidis YC, Havel PJ, Stanhope KL, O'Brien DM, Hopkins SE, Boyer BB, Tiwari HK (2013). Evidence for novel genetic loci associated with metabolic traits in Yup’ik people. American Journal of Human Biology. 25: 673-80.

 

Lemas DJ, Klimentidis YC, Weiner HH, O’Brien DM, Hopkins S, Stanhope KL, Havel PJ, Allison DB, Fernandez JR, Tiwari HK, Boyer BB (2013). Obesity polymorphisms identified in genome-wide association studies interact with n-3 polyunsaturated fatty acid intake and modify the genetic association with adiposity phenotypes in Yup'ik people. Genes and Nutrition. 8: 495-505.

 

Malek AJ, Klimentidis YC, Kell KP, Fernandez JR (2013). Associations of the lactase persistence allele and lactose intake with body composition among multiethnic children. Genes and Nutrition. 8: 487-94.

 

Vazquez AI, de los Campos G, Klimentidis YC, Rosa GMJ, Gianola D, Yi N, Allison DB (2012). A Comprehensive Genetic Approach for Improving Prediction of Skin Cancer Risk in Humans. Genetics. 192(4):1493-502.

 

De los Campos G, Klimentidis YC, Vazquez AI, Allison DB (2012). Prediction of expected years of life using whole-genome markers. PLoS One. 7(7):e40964.

 

Klimentidis YC, Dulin-Keita A, Casazza K, Willig A, Allison DB, Fernandez JR (2012) Genetic admixture, social-behavioral factors, and body composition are associated with blood pressure differently by racial-ethnic group among children. Journal of Human Hypertension. 26(2):98-107

 

Quillen EE, Marc Bauchet M, Bigham AW, Delgado-Burbano ME, Faust F, Klimentidis YC, Mao X, Stoneking M, and Shriver MD (2012). OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and Europeans. Human Genetics. 131(7):1073-80.

 

Fernandez JR, Klimentidis YC, Dulin-Keita A, Casazza K (2012). Genetic influences in childhood obesity: recent progress and recommendations for experimental designs. International Journal of Obesity. 36(4):479-84.

 

Gomez-Rubio P, Klimentidis YC, Cantu-Soto E, Meza-Montenegro MM, Billheimer D, Lu Z, Chen Z, Klimecki W (2012). Indigenous American ancestry is associated with arsenic methylation efficiency in an admixed population of northwest Mexico. Journal of Toxicology and Environmental Health A. 75(1): 36-49.

 

Klimentidis YC, Chen GB, Lopez-Alarcon M, Harris J, Duarte C, Fernandez JR (2011). Associations of Obesity Genes with Obesity-related Outcomes in Multiethnic Children. Archives of Medical Research. 42(6): 509-14.

 

Duarte CW, Klimentidis YC, Harris J, Cardel M, Fernandez JR (2011) A Hybrid Bayesian Network/Structural Equation (BN/SEM) Modeling Approach for Detecting Physiological Networks for Obesity-related Genetic Variants. Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 2011:696-702.

 

Klimentidis YC, Aissani B, Shriver MD, Allison DB, Sadeep Shrestha (2011). Natural Selection among Eurasians at genomic regions associated with HIV-1 control. BMC Evolutionary Biology. 11: 173.

 

Makowsky R, Pajewski N, Klimentidis YC,  Vazquez AI, Duarte C, Allison DB, de los Campos G (2011) Beyond missing heritability: Prediction of complex traits. PLoS Genetics 7(4): e1002051

 

Klimentidis YC, Abrams M, Wang J, Fernandez JR, Allison DB (2011) Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions. Human Genetics. 129: 407-418.

 

Klimentidis YC, T. Mark Beasley, Hui-Yi Lin, Giulianna Murati, Gregory E. Glass, Marcus Guyton, Wendy Newton, Matthew Jorgensen, Steven B. Heymsfield, Joseph Kemnitz, Lynn Fairbanks, & Allison DB (2011) Canaries in the Coal Mine: A Cross-Species Analysis of the Plurality of Obesity Epidemics. Proceedings of the Royal Society, B. 278(1712):1626-32

 

Klimentidis YC, Divers J, Casazza K, Allison DB, Fernandez JR (2011) Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children. Human Genomics. Jan 5(2):79-89.

 

De Luca M, Klimentidis YC, Casazza K, Chambers MM, Cho R, Harbison ST, Jumbo-Lucioni P, Zhang S, Leips J, and Fernandez JR. (2010) A conserved role for syndecan family members in the regulation of whole-body energy metabolism. PLoS One 5(6): e11286

 

Friedrich TC, Piaskowski SM, Léon EJ, Furlott JR, Maness NJ, Weisgrau KL, MacNair CE, Weiler AM, Loffredo JT, Reynolds MR, Williams KY, Klimentidis YC, Wilson NA, Allison DB, and Rakasz EG. (2010) High viremia is associated with high levels of in vivo MHC-I downregulation in rhesus macaques infected with SIVmac239. Journal of Virology, 84(10):5443-7.

 

Martins MA, Wilson NA, Reed JS, Ahn CD, Klimentidis YC, Allison DB, and Watkins DI (2010) T-cell correlates of vaccine efficacy after a heterologous SIV challenge. Journal of Virology, 84(9):4352-65.

 

Valentine LE, Loffredo JT, Bean AT, León EJ, MacNair CE, Beal DR, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC, O'Connor DH, Allison DB, and Watkins DI (2009) Infection with "escaped" virus variants impairs control of SIVmac239 replication in Mamu-B*08+ macaques. Journal of Virology, 83(22) 11514-27.

 

Klimentidis YC, Miller G, Shriver MD (2009) The relationship between European genetic admixture and body composition among Hispanics and Native Americans. American Journal of Human Biology, 21(3):377-382.

 

Klimentidis YC, Shriver MD (2009) Estimating genetic admixture proportions from faces. PLoS One, 4(2): e4460.

 

Klimentidis YC, Miller G, Shriver MD (2009) Genetic admixture, self-reported ethnicity, self-estimated admixture, and skin pigmentation among Hispanics and Native Americans. American Journal of Physical Anthropology, 138(4): 375-83.

 

Hadsell DL, Bonnette S, George J, Torres D, Klimentidis Y, Gao S, Haney PM, Summy-Long J, Soloff MS, Parlow AF, Sirito M, Sawadogo M (2003) Diminished milk synthesis in upstream stimulatory factor 2 null mice is associated with decreased circulating oxytocin and decreased mammary gland expression of eukaryotic initiation factors 4E and 4G. Molecular Endocrinology 17(11):2251-67.

 

Hadsell DL, Alexeenko T, Klimentidis Y, Torres D, Lee AV (2001) Inability of overexpressed des(1-3) human insulin-like growth factor I (IGF-I) to inhibit forced mammary gland involution is associated with decreased expression of IGF signaling molecules. Endocrinology 142: 1479-88.